HUMIX GUT-ON-A-CHIP

Summary of the technology

HUMIX is a modular, microfluidics-based model which allows co-culture of human and microbial cells under conditions representative of the gastrointestinal human–microbe interface.

Nature Communications:
https://www.nature.com/articles/ncomms11535

University of Luxembourg

Details of the Technology Offer

The system facilitates investigations of host–microbe molecular interactions and provides insights into a range of fundamental research questions linking the gastrointestinal microbiome to human health and disease. Different development based on HUMIX are:

microGUT is an artificial digestive tract the size of a shoebox, which reproduces the environmental conditions inside the gut and allows the study of the human gastrointestinal microbes along the entire intestinal tract.

NutriHumix is a combined in silico and in vitro system to model the interactions between a patient’s diet, their microbiome, and their body systems . Personalized, combinational approach to cancer care in order to select appropriate cancer therapeutic regimens.

ADVANTAGES
• HuMiX & microGUT models are the closest representative of the human GIT
• The combined in silico and in vitro modelling system provides robust data
• Capable of mimicking the anaerobic gastrointestinal microenvironment
• Modular technology that can analyze high-throughput data


AREAS OF APPLICATION AND IP STATUS
Drug discovery, Food & Drink for Health Market, Oral Nutritional Supplement Market

Nature Communications:
https://www.nature.com/articles/ncomms11535

The system is subject of the following patent applications: EP13713844.2, US14/389,137, EU16725161.0, US15/576,590, US16/348,835, PCT/EP2019/081424

Related Keywords

  • Biological Sciences
  • Medicine, Human Health
  • Diagnostics, Diagnosis
  • Agriculture and Marine Resources
  • Food and Beverages
  • medical technology

About University of Luxembourg

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